The cleaning industry does not currently have a standard on effective infection prevention and control for cleaners who maintain the built environment. This standard will focus on the principles, methods, and processes to clean and sanitize the built environment. We define the built environment as materials, building assemblies, structures, furniture, fixtures, and equipment located inside a building envelope. Further, this standard will focus on how to establish goals and verify results in reaching a hygienically clean outcome. An ANSI Standard would provide guidance on proper cleaning and remediation procedures with antimicrobial biocides.